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1

A systematic reactor design approach for the synthesis of active pharmaceutical ingredients

Emenike, Victor N., Schenkendorf, René, Krewer, Ulrike

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

2

Model-based optimization of biopharmaceutical manufacturing in Pichia pastoris based on dynamic flux balance analysis

Emenike, Victor N., Schenkendorf, René, Krewer, Ulrike

Journal:

Computers & Chemical Engineering

Year:

2018

Language:

english

File:

PDF, 907 KB

english, 2018

3

Model-Based Tools for Pharmaceutical Manufacturing Processes

Schenkendorf, René, Gerogiorgis, Dimitrios I., Mansouri, Seyed Soheil, Gernaey, Krist V.

Journal:

Year:

2020

Language:

english

File:

PDF, 164 KB

english, 2020

4

Influence of non-linearity to the Optimal Experimental Design demonstrated by a biological system

Schenkendorf, René, Kremling, Andreas, Mangold, Michael

Journal:

Mathematical and Computer Modelling of Dynamical Systems

Year:

2012

Language:

english

File:

PDF, 571 KB

english, 2012

5

Online model selection approach based on Unscented Kalman Filtering

Schenkendorf, René, Mangold, Michael

Journal:

Journal of Process Control

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

6

Parameter identification for ordinary and delay differential equations by using flat inputs

Schenkendorf, René, Mangold, Michael

Journal:

Theoretical Foundations of Chemical Engineering

Year:

2014

Language:

english

File:

PDF, 923 KB

english, 2014

7

[IEEE 2016 Conference on Control and Fault-Tolerant Systems (SysTol) - Barcelona, Spain (2016.9.7-2016.9.9)] 2016 3rd Conference on Control and Fault-Tolerant Systems (SysTol) - Supporting the shift towards continuous pharmaceutical manufacturing by condition monitoring

Schenkendorf, Rene

Year:

2016

Language:

english

File:

PDF, 180 KB

english, 2016

8

Qualitative and Quantitative Optimal Experimental Design for Parameter Identification of a MAP Kinase Model

Schenkendorf, René, Mangold, Michael

Journal:

IFAC Proceedings Volumes

Year:

2011

Language:

english

File:

PDF, 229 KB

english, 2011

9

Parameter Identification Of Time-Delay Systems: A Flatness Based Approach

Schenkendorf, René, Reichl, Udo, Mangold, Michael

Journal:

IFAC Proceedings Volumes

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

10

Efficient Global Sensitivity Analysis of 3D Multiphysics Model for Li-Ion Batteries

Lin, Nan, Xie, Xiangzhong, Schenkendorf, René, Krewer, Ulrike

Journal:

Journal of The Electrochemical Society

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

11

[Computer Aided Chemical Engineering] 27th European Symposium on Computer Aided Process Engineering Volume 40 || An Efficient Polynomial Chaos Expansion Strategy for Active Fault Identification of Chemical Processes

Schenkendorf, René

Year:

2017

Language:

english

File:

PDF, 326 KB

english, 2017

12

Efficient sensitivity analysis and interpretation of parameter correlations in chemical engineering

Xie, Xiangzhong, Schenkendorf, René, Krewer, Ulrike

Journal:

Reliability Engineering & System Safety

Year:

2018

Language:

english

File:

PDF, 3.34 MB

english, 2018

13

State-of-Health Identification of Lithium-Ion Batteries Based on Nonlinear Frequency Response Analysis: First Steps with Machine Learning

Harting, Nina, Schenkendorf, René, Wolff, Nicolas, Krewer, Ulrike

Journal:

Applied Sciences

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

14

The Impact of Global Sensitivities and Design Measures in Model-Based Optimal Experimental Design

Schenkendorf, René, Xie, Xiangzhong, Rehbein, Moritz, Scholl, Stephan, Krewer, Ulrike

Journal:

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

15

An Efficient Polynomial Chaos Expansion Strategy for Active Fault Identification of Chemical Processes

Schenkendorf, René, Xie, Xiangzhong, Krewer, Ulrike

Journal:

Computers & Chemical Engineering

Year:

2018

File:

PDF, 1.28 MB

2018

16

An Efficient Polynomial Chaos Expansion Strategy for Active Fault Identification of Chemical Processes

Schenkendorf, René, Xie, Xiangzhong, Krewer, Ulrike

Journal:

Computers & Chemical Engineering

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

17

Robust dynamic optimization of enzyme-catalyzed carboligation: a point estimate-based back-off approach

Emenike, Victor N., Xiangzhong, Xie, Schenkendorf, René, Spiess, Antje, Krewer, Ulrike

Journal:

Computers & Chemical Engineering

Year:

2018

Language:

english

File:

PDF, 10.34 MB

english, 2018

18

Model-based tools for optimal experiments in bioprocess engineering

Abt, Vinzenz, Barz, Tilman, Cruz, Nicolay, Herwig, Christoph, Kroll, Paul, Möller, Johannes, Pörtner, Ralf, Schenkendorf, René

Journal:

Current Opinion in Chemical Engineering

Year:

2018

Language:

english

File:

PDF, 1008 KB

english, 2018

19

Model‐based Uncertainty Quantification for the Product Properties of Lithium‐Ion Batteries

Laue, Vincent, Schmidt, Oke, Dreger, Henning, Xie, Xiangzhong, Röder, Fridolin, Schenkendorf, Rene, Kwade, Arno, Krewer, Ulrike

Journal:

Energy Technology

Year:

2019

Language:

english

File:

PDF, 1.79 MB

english, 2019

20

Novel electrodynamic oscillation technique enables enhanced mass transfer and mixing for cultivation in micro‐bioreactor

Frey, Lasse Jannis, Vorländer, David, Rasch, Detlev, Ostsieker, Hendrik, Müller, Bernhard, Schulze, Moritz, Schenkendorf, René, Mayr, Torsten, Grosch, Jan‐Hendrik, Krull, Rainer

Journal:

Biotechnology Progress

Year:

2019

Language:

english

File:

PDF, 4.02 MB

english, 2019

21

Toward a Comprehensive and Efficient Robust Optimization Framework for (Bio)chemical Processes

Xie, Xiangzhong, Schenkendorf, René, Krewer, Ulrike

Journal:

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

22

The Effect of Correlated Kinetic Parameters on (Bio)Chemical Reaction Networks

Xie, Xiangzhong, Schenkendorf, René, Krewer, Ulrike

Journal:

Chemie Ingenieur Technik

Year:

2019

Language:

english

File:

PDF, 241 KB

english, 2019

23

Robust optimization of a pharmaceutical freeze-drying process under non-Gaussian parameter uncertainties

Xie, Xiangzhong, Schenkendorf, René

Journal:

Chemical Engineering Science

Year:

2019

Language:

english

File:

PDF, 1.95 MB

english, 2019

24

Robust optimization of a pharmaceutical freeze-drying process under non-Gaussian parameter uncertainties

Xie, Xiangzhong, Schenkendorf, René

Journal:

Chemical Engineering Science

Year:

2019

File:

PDF, 1.95 MB

2019

25

Robust Process Design in Pharmaceutical Manufacturing under Batch-to-Batch Variation

Xie, Xiangzhong, Schenkendorf, René

Journal:

Year:

2019

Language:

english

File:

PDF, 803 KB

english, 2019

26

Robust Optimization of Dynamical Systems with Correlated Random Variables using the Point Estimate Method ⁎ ⁎Financial support of Promotionsprogramm “μ-Props” by MWK Niedersachsen is gratefully acknowledged.

Xie, Xiangzhong, Krewer, Ulrike, Schenkendorf, René

Journal:

IFAC-PapersOnLine

Year:

2018

Language:

english

File:

PDF, 906 KB

english, 2018

27

Flatness-Based Design of Experiments for Model Selection

Schulze, Moritz, Schenkendorf, René

Journal:

IFAC-PapersOnLine

Year:

2018

Language:

english

File:

PDF, 491 KB

english, 2018

28

Moment-Independent Sensitivity Analysis of Enzyme-Catalyzed Reactions with Correlated Model Parameters ⁎ ⁎Funding of Promotionsprogramm “μ-Props” by MWK Niedersachsen is gratefully acknowledged. Xiangzhong Xie is also a member of the International Max Planck Research School for Advanced Methods in Process and Systems Engineering, 39106 Magdeburg, Germany

Xie, Xiangzhong, Ohs, Rüdiger, Spieß, Antje, Krewer, Ulrike, Schenkendorf, René

Journal:

IFAC-PapersOnLine

Year:

2018

Language:

english

File:

PDF, 902 KB

english, 2018